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Acitrom uses: Nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the UK), which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body's natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism.Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain, causing a stroke. Acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. Acenocoumarol works by preventing the vitamin K dependent production of the clotting factors described above. Acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.Acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. For this reason, when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.The anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. This time is expressed as the International Normalised Ratio (INR). Your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.What is it used for?Treating and preventing blood clots in the blood vessels, for example in the following cases:Preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves Treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) Treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism)

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for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. this is known as a thromboembolism. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. this is the body's natural way of repairing itself. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. sometimes, however, a blood clot can form abnormally within the blood vessels. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. these clots can break off and travel to the lungs (pulmonary embolism). acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. vitamin k is essential for their production. clotting factors are proteins that are produced by the liver. it is used to stop blood clots forming within the blood vessels.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is usually due to a disturbance in the blood flow within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.some people have an increased tendency for blood clots to form within the blood vessels.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. this time is expressed as the international normalised ratio (inr). fibrin binds the platelets together, forming a blood clot. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). clots in the heart can detach and travel to the brain, causing a stroke
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some people have an increased tendency for blood clots to form within the blood vessels. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. fibrin binds the platelets together, forming a blood clot. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. sometimes, however, a blood clot can form abnormally within the blood vessels. these clots can break off and travel to the lungs (pulmonary embolism). slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. this time is expressed as the international normalised ratio (inr). clotting factors are proteins that are produced by the liver. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. it is used to stop blood clots forming within the blood vessels. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. this is known as a thromboembolism. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. clots in the heart can detach and travel to the brain, causing a stroke. vitamin k is essential for their production. this is the body's natural way of repairing itself. this is usually due to a disturbance in the blood flow within the blood vessels
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for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. it is used to stop blood clots forming within the blood vessels.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. these clots can break off and travel to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. vitamin k is essential for their production. clots in the heart can detach and travel to the brain, causing a stroke. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. clotting factors are proteins that are produced by the liver. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. this time is expressed as the international normalised ratio (inr).some people have an increased tendency for blood clots to form within the blood vessels. this is usually due to a disturbance in the blood flow within the blood vessels. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. sometimes, however, a blood clot can form abnormally within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. fibrin binds the platelets together, forming a blood clot. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. this is known as a thromboembolism. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is the body's natural way of repairing itself.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up
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acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). it is used to stop blood clots forming within the blood vessels. fibrin binds the platelets together, forming a blood clot.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. sometimes, however, a blood clot can form abnormally within the blood vessels. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. this is the body's natural way of repairing itself. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. this time is expressed as the international normalised ratio (inr). this is known as a thromboembolism. clots in the heart can detach and travel to the brain, causing a stroke. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. clotting factors are proteins that are produced by the liver. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. vitamin k is essential for their production. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).some people have an increased tendency for blood clots to form within the blood vessels. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. these clots can break off and travel to the lungs (pulmonary embolism). this is usually due to a disturbance in the blood flow within the blood vessels. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues
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sometimes, however, a blood clot can form abnormally within the blood vessels. vitamin k is essential for their production.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. this is known as a thromboembolism. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. this is usually due to a disturbance in the blood flow within the blood vessels. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. this is the body's natural way of repairing itself. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. these clots can break off and travel to the lungs (pulmonary embolism). clotting factors are proteins that are produced by the liver.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). clots in the heart can detach and travel to the brain, causing a stroke. this time is expressed as the international normalised ratio (inr). it is used to stop blood clots forming within the blood vessels. fibrin binds the platelets together, forming a blood clot. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted.some people have an increased tendency for blood clots to form within the blood vessels
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the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. fibrin binds the platelets together, forming a blood clot. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. it is used to stop blood clots forming within the blood vessels.some people have an increased tendency for blood clots to form within the blood vessels. clotting factors are proteins that are produced by the liver. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. this is the body's natural way of repairing itself. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. this is usually due to a disturbance in the blood flow within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. this time is expressed as the international normalised ratio (inr). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). sometimes, however, a blood clot can form abnormally within the blood vessels. this is known as a thromboembolism. clots in the heart can detach and travel to the brain, causing a stroke. these clots can break off and travel to the lungs (pulmonary embolism). vitamin k is essential for their production. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus
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this time is expressed as the international normalised ratio (inr). these clots can break off and travel to the lungs (pulmonary embolism). blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. sometimes, however, a blood clot can form abnormally within the blood vessels. vitamin k is essential for their production. clotting factors are proteins that are produced by the liver. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. it is used to stop blood clots forming within the blood vessels.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.some people have an increased tendency for blood clots to form within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. clots in the heart can detach and travel to the brain, causing a stroke. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is the body's natural way of repairing itself. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. this is known as a thromboembolism. this is usually due to a disturbance in the blood flow within the blood vessels. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. fibrin binds the platelets together, forming a blood clot
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heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. vitamin k is essential for their production.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.some people have an increased tendency for blood clots to form within the blood vessels. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. clotting factors are proteins that are produced by the liver. this is known as a thromboembolism. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. clots in the heart can detach and travel to the brain, causing a stroke. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. it is used to stop blood clots forming within the blood vessels. this is the body's natural way of repairing itself. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. this is usually due to a disturbance in the blood flow within the blood vessels. these clots can break off and travel to the lungs (pulmonary embolism). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. sometimes, however, a blood clot can form abnormally within the blood vessels. fibrin binds the platelets together, forming a blood clot. this time is expressed as the international normalised ratio (inr)
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the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. fibrin binds the platelets together, forming a blood clot. this time is expressed as the international normalised ratio (inr). without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. these clots can break off and travel to the lungs (pulmonary embolism).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.some people have an increased tendency for blood clots to form within the blood vessels. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). this is usually due to a disturbance in the blood flow within the blood vessels. this is the body's natural way of repairing itself. clots in the heart can detach and travel to the brain, causing a stroke. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. clotting factors are proteins that are produced by the liver. sometimes, however, a blood clot can form abnormally within the blood vessels. vitamin k is essential for their production. this is known as a thromboembolism. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. it is used to stop blood clots forming within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k
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