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Acitrom uses: Nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the UK), which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body's natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism.Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain, causing a stroke. Acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. Acenocoumarol works by preventing the vitamin K dependent production of the clotting factors described above. Acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.Acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. For this reason, when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.The anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. This time is expressed as the International Normalised Ratio (INR). Your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.What is it used for?Treating and preventing blood clots in the blood vessels, for example in the following cases:Preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves Treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) Treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism)

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blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. these clots can break off and travel to the lungs (pulmonary embolism). slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is the body's natural way of repairing itself. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. it is used to stop blood clots forming within the blood vessels. vitamin k is essential for their production. this is known as a thromboembolism. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. fibrin binds the platelets together, forming a blood clot. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. this is usually due to a disturbance in the blood flow within the blood vessels. clots in the heart can detach and travel to the brain, causing a stroke. clotting factors are proteins that are produced by the liver.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. sometimes, however, a blood clot can form abnormally within the blood vessels. this time is expressed as the international normalised ratio (inr). without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.some people have an increased tendency for blood clots to form within the blood vessels
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acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. this time is expressed as the international normalised ratio (inr). the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. these clots can break off and travel to the lungs (pulmonary embolism).what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. this is the body's natural way of repairing itself. vitamin k is essential for their production. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. this is usually due to a disturbance in the blood flow within the blood vessels.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. clots in the heart can detach and travel to the brain, causing a stroke. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. this is known as a thromboembolism. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. fibrin binds the platelets together, forming a blood clot. it is used to stop blood clots forming within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. sometimes, however, a blood clot can form abnormally within the blood vessels. clotting factors are proteins that are produced by the liver. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.some people have an increased tendency for blood clots to form within the blood vessels
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this is usually due to a disturbance in the blood flow within the blood vessels.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. this is known as a thromboembolism. these clots can break off and travel to the lungs (pulmonary embolism). this time is expressed as the international normalised ratio (inr). acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. clots in the heart can detach and travel to the brain, causing a stroke.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. vitamin k is essential for their production. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. fibrin binds the platelets together, forming a blood clot. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.some people have an increased tendency for blood clots to form within the blood vessels. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). it is used to stop blood clots forming within the blood vessels. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. clotting factors are proteins that are produced by the liver. sometimes, however, a blood clot can form abnormally within the blood vessels. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. this is the body's natural way of repairing itself. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin
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without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. vitamin k is essential for their production. clots in the heart can detach and travel to the brain, causing a stroke. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. sometimes, however, a blood clot can form abnormally within the blood vessels. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. fibrin binds the platelets together, forming a blood clot. these clots can break off and travel to the lungs (pulmonary embolism). this is the body's natural way of repairing itself.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). it is used to stop blood clots forming within the blood vessels. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. this is known as a thromboembolism. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted.some people have an increased tendency for blood clots to form within the blood vessels. this time is expressed as the international normalised ratio (inr). this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). clotting factors are proteins that are produced by the liver. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. this is usually due to a disturbance in the blood flow within the blood vessels. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above
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a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. clotting factors are proteins that are produced by the liver. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus.some people have an increased tendency for blood clots to form within the blood vessels.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is the body's natural way of repairing itself. this is known as a thromboembolism.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. this time is expressed as the international normalised ratio (inr). the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. fibrin binds the platelets together, forming a blood clot. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. it is used to stop blood clots forming within the blood vessels. vitamin k is essential for their production.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. this is usually due to a disturbance in the blood flow within the blood vessels. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. these clots can break off and travel to the lungs (pulmonary embolism). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. clots in the heart can detach and travel to the brain, causing a stroke. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. sometimes, however, a blood clot can form abnormally within the blood vessels
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clots in the heart can detach and travel to the brain, causing a stroke. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. these clots can break off and travel to the lungs (pulmonary embolism). this time is expressed as the international normalised ratio (inr). heart valve disease can have the same effect, particularly if artificial heart valves have been fitted.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. this is the body's natural way of repairing itself. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. clotting factors are proteins that are produced by the liver. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.some people have an increased tendency for blood clots to form within the blood vessels. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. fibrin binds the platelets together, forming a blood clot.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. it is used to stop blood clots forming within the blood vessels. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. vitamin k is essential for their production. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. this is known as a thromboembolism. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. sometimes, however, a blood clot can form abnormally within the blood vessels. this is usually due to a disturbance in the blood flow within the blood vessels. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up
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for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. this is the body's natural way of repairing itself. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.some people have an increased tendency for blood clots to form within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. sometimes, however, a blood clot can form abnormally within the blood vessels. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. fibrin binds the platelets together, forming a blood clot. clots in the heart can detach and travel to the brain, causing a stroke. this is known as a thromboembolism. clotting factors are proteins that are produced by the liver. this time is expressed as the international normalised ratio (inr). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. vitamin k is essential for their production. it is used to stop blood clots forming within the blood vessels. this is usually due to a disturbance in the blood flow within the blood vessels.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. these clots can break off and travel to the lungs (pulmonary embolism).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up
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the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. these clots can break off and travel to the lungs (pulmonary embolism). this is usually due to a disturbance in the blood flow within the blood vessels. it is used to stop blood clots forming within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). this is the body's natural way of repairing itself. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. vitamin k is essential for their production. clotting factors are proteins that are produced by the liver. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. sometimes, however, a blood clot can form abnormally within the blood vessels. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. this is known as a thromboembolism. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.some people have an increased tendency for blood clots to form within the blood vessels. fibrin binds the platelets together, forming a blood clot. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. clots in the heart can detach and travel to the brain, causing a stroke. this time is expressed as the international normalised ratio (inr)
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acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). it is used to stop blood clots forming within the blood vessels. this is known as a thromboembolism. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. these clots can break off and travel to the lungs (pulmonary embolism). fibrin binds the platelets together, forming a blood clot. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. this time is expressed as the international normalised ratio (inr). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. this is the body's natural way of repairing itself. sometimes, however, a blood clot can form abnormally within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. clots in the heart can detach and travel to the brain, causing a stroke. this is usually due to a disturbance in the blood flow within the blood vessels.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin.some people have an increased tendency for blood clots to form within the blood vessels. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). clotting factors are proteins that are produced by the liver. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. vitamin k is essential for their production
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